Infections of the gastrointestinal tract belong to the most common diseases of our modern society. In the industrial nations alone they are by now the second frequent disease in childhood.
The diagnostics of infectious intestinal diseases belongs to the most frequent demands on a medical microbiological lab has to face. Knowledge of pathogenesis, epidemiology and diagnostics of these diseases has grown considerably over the last years, along with the list of possible agents. Besides the classical methods of microbiology immunological tests like ELISA and immunochromatographic rapid tests play a more and more important role in the microbiological lab. They have the big advantage of showing also those germs that are no longer capable to multiply as a cause for a certain disease.
Most commonly an infection, caused by enteropathogenic microorganisms, disturbs the normal barrier function of the intestinal mucosa, normally only temporarily. Such enteropathogenic species are found among bacteria, viruses and protozoans. As far as infants are concerned, rotaviruses are among the most important causes of the infectious enteritis. Besides that especially the Noroviruses that can’t be cultivated play an important role among the viral agents, besides Astro- and Adenoviruses.
Among the protozoans Giardia lamblia, Entamoeba histolytica, Cryptosporidia, Cyclospora cayetanensis and occasionally Blastocystis hominis are the most important diarrhoea agents. As far as bacteria are concerned, Campylobacter causes by now just as many diseases as salmonella, besides a large number of other pathogenic bacteria species.
As far as stool diagnostics is concerned, R-Biopharm offers a wide range of test kits for the specific evidence of antigens of the different pathogenic agents in stool specimens. The ELISA systems are available under the name RIDASCREEN®, the immunochromatographic rapid tests under the name RIDA®QUICK. The rapid tests are offered as dipstick as well as in the practical cassette format.